产品货号：
Z19632
中文名称：
KREMEN2抗体
英文名称：
Anti-KREMEN2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-KREMEN2 Antibody |
| 指标别名 | KRM2;KRM2;Kremen protein 2;Dickkopf receptor 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC |
| 基因名称 | KREMEN2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-KREMEN2 antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human KREMEN2.The immunogen is located within amino acids 390-440 of KREMEN2. |
| 计算分子量 | 49kDa |
| 成分 | KREMEN2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | KREMEN2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle,WSC and CUB domains and an intracellular region without any conserved motifs.Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1,2,and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt,Frizzled,and the LDL receptor related protein 5/6 (LRP5/6) co-receptor.Recent experiments have shown that KREMEN2 is a regulator of bone remodeling and raise the possibility that antagonizing KREMEN2 might prove beneficial in patients with bone loss disorders. |
| Uniprot ID | Q8NCW0 |
| 基因名全称 | Kringle containing transmembrane protein 2 |
| 蛋白名全称 | Kringle containing transmembrane protein 2 |
| 推荐稀释比 | WB:1～2μg/mL;ICC:5μg/mL.Antibody validated:Western Blot in human,mouse and rat samples;Immunocytochemistry in human samples.All other applications and species not yet tested. |
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